How Much Does a Physician Assistant Make in St. Louis, MO in 2026?
Typical pay for Physician Assistants in St. Louis, from federal wage data (May 2025), with the ten-year trend and how the city compares across Missouri.
BLS OES May 2025 · St. Louis metro area
A typical Physician Assistant in St. Louis, Missouri earns $65.44 per hour, or $136,120 per year, according to the latest government wage data for the area (May 2025). Calculated from the annual figure, that is roughly $11,343 a month. Entry-level positions typically offer around $77,620, and the top 10% of earners make over $170,960.
That pay is 1% above the Missouri figure of $135,130 and right at the national figure of $135,880. St. Louis ranks 4th of 8 metro areas in Missouri for Physician Assistant pay. About 1,260 Physician Assistants work in the St. Louis area.
Physician Assistant pay in St. Louis at a glance
- Typical pay is $65.44 an hour, or $136,120 a year.
- That is 1% above the Missouri figure, ranking 4th of 8 metro areas in the state.
- Entry-level positions typically offer around $77,620; the top 10% make over $170,960.
- Typical pay rose +43% from 2015 to 2025, against +45% for Missouri as a whole.
BLS OES May 2025
How much does a Physician Assistant make in St. Louis?
Pay in St. Louis runs from entry-level positions at around $37.32 an hour to more than $82.19 for the top 10% of earners. The table sets each career stage against the Missouri and national figures.
Physician Assistant pay by career stage in St. Louis
| Career stage | St. Louis | Missouri | United States |
|---|---|---|---|
| Starting out | $77,620$37.32 an hour | $82,690$39.76 an hour | $99,380$47.78 an hour |
| First years | $124,080$59.65 an hour | $121,680$58.50 an hour | $120,670$58.02 an hour |
| Typical Physician Assistant | $136,120$65.44 an hour | $135,130$64.96 an hour | $135,880$65.33 an hour |
| Experienced | $164,700$79.18 an hour | $163,170$78.45 an hour | $163,980$78.84 an hour |
| Top 10% | $170,960$82.19 an hour | $169,650$81.56 an hour | $190,280$91.48 an hour |
BLS OES May 2025 · city figures cover the St. Louis area as BLS defines it
Physician Assistant pay growth in St. Louis
Typical (median) annual wage for Physician Assistants in the St. Louis area · BLS OES May estimates, 2015 to 2025 · hover a bar for the year-over-year change
In 2015, typical Physician Assistant pay in St. Louis was $95,270 a year. By 2025 it had reached $136,120, a change of +43%, compared with +45% for Missouri over the same years.
How St. Louis compares with other Missouri cities
Joplin pays Physician Assistants the most in Missouri at $150,300 a year, $14,180 more than St. Louis. The lowest-paying area in the state is Springfield at $129,270.
| # | City | Typical pay | Hourly | Vs St. Louis | Physician Assistants employed |
|---|---|---|---|---|---|
| 1 | Joplin | $150,300 | $72.26 | +10% | 70 |
| 2 | Cape Girardeau | $141,080 | $67.83 | +4% | 40 |
| 3 | St. Joseph | $138,060 | $66.38 | +1% | 50 |
| 4 | St. Louis | $136,120 | $65.44 | this city | 1,260 |
| 5 | Jefferson City | $135,340 | $65.07 | -1% | 40 |
| 6 | Kansas City | $133,350 | $64.11 | -2% | 540 |
| 7 | Columbia | $132,220 | $63.57 | -3% | 140 |
| 8 | Springfield | $129,270 | $62.15 | -5% | 300 |
Every metro area in Missouri with Physician Assistant wage data · BLS OES May 2025 · Missouri typical pay $135,130
Is St. Louis a good place to work as a Physician Assistant?
Physician Assistant pay in St. Louis sits close to the national figure: $136,120 a year, right at the national rate. For every 1,000 jobs in the St. Louis area, about 0.9 are Physician Assistant positions; nationally, the figure is closer to 1.0. Physician Assistant jobs make up about the same share of the job market as they do across the country.
Frequently asked questions
- How much does a Physician Assistant make in St. Louis, MO?
- A typical Physician Assistant in St. Louis earns $136,120 a year, or $65.44 an hour, according to BLS wage data for May 2025. Entry-level pay runs about $77,620 and the top 10% earn over $170,960.
- How much does a Physician Assistant make an hour in St. Louis?
- Typical hourly pay for Physician Assistants in St. Louis is $65.44. Entry-level hourly pay runs about $37.32, and the top 10% earn over $82.19 an hour.
- What is the starting pay for a Physician Assistant in St. Louis?
- Entry-level Physician Assistant positions in St. Louis typically offer around $37.32 an hour, or $77,620 a year.
- Is Physician Assistant pay in St. Louis higher than in the rest of Missouri?
- St. Louis pay is 1% above the Missouri figure of $135,130 a year, ranking 4th of 8 metro areas in the state. Joplin pays the most in Missouri at $150,300.