How Much Does an NP Make in Missouri in 2026?

A typical NP in Missouri earns about $62.47 per hour ($129,930 per year), per the latest government wage data (May 2025). That works out to roughly $10,828 a month, or $2,499 a week, both figures calculated from the annual figure. Full-time NPs across the state can expect pay to cluster near this figure, with some variation by city and setting.

Nationally, typical pay for NPs is $63.61 an hour ($132,300 a year), so Missouri runs about 2% below that figure. The state ranks 35th out of 51 states and the District of Columbia for NP pay. Missouri employs 7,710 NPs, a workforce size that puts these figures on solid footing across the state.

Entry-level positions in Missouri typically offer around $48.39 an hour ($100,650 a year), based on the latest wage data. Pay for these NPs tends to move toward the state's typical figure of $129,930 within a few years on the job. Setting plays a role too, with hospital and specialty roles often paying more than smaller clinics early on.

Experienced NPs in Missouri often earn upwards of $144,640 a year ($69.54 an hour), and the top 10% of earners make over $162,060. That leaves a spread of $61,410 between entry-level and top pay. Setting, years of experience, and city all factor into where an individual NP lands within that range.

Missouri NP pay rose from $91,020 in 2015 to $129,930 in 2025, a gain of $38,910 over the decade. That's a 43% increase in ten years. The rise was not perfectly steady; pay dipped slightly in 2021 before climbing again through 2025.

That climb outpaced the national rise of 35% over the same ten years. For someone starting an NP career in Missouri now, the numbers show pay has moved up substantially over the past decade. Recent years show the fastest gains, with pay climbing from $117,910 in 2023 to $129,930 in 2025. Future pay is never guaranteed, but the trend has been upward.

NP pay runs highest in St. Louis, where the typical figure is $131,580 a year ($63.26 an hour), about 1% above the statewide figure. Kansas City follows closely at $130,760 a year, and Cape Girardeau and Columbia also post figures above $128,900. These figures cover each city's full metro area.

At the other end, Springfield posts the lowest figure among Missouri's listed cities, at $125,630 a year ($60.40 an hour), a spread of $5,950 between the highest and lowest metro areas. St. Louis also carries the largest NP workforce in the state, with 3,430 workers. That gap in pay often tracks differences in local living costs rather than anything else.

Missouri's neighbors show a mixed picture. Oklahoma pays NPs the most nearby, at $133,390 a year, about 3% above Missouri's figure, while Nebraska and Illinois also edge slightly higher. On the lower end, Tennessee's figure of $117,590 runs about 9% below Missouri's. NP licensure earned in one state can often be transferred or endorsed into a neighboring state, easing a move across state lines.

A typical NP in Missouri earns about $129,930 a year as of May 2025, up 43% over the past decade from $91,020 in 2015. Pay varies by city and experience level, with St. Louis and Kansas City running highest and Springfield lowest. Readers weighing a move or a new license should check Missouri's state licensing or registry page for current requirements, and the city pages for local pay figures.