How Much Does an LPN Make in Mississippi in 2026?

A typical LPN in Mississippi earns about $24.14 per hour ($50,220 per year), per the latest government wage data (May 2025). That works out to roughly $4,185 a month and $966 a week, both figures calculated from the annual figure above. These numbers reflect pay across the state's hospitals, nursing homes, and outpatient clinics.

That figure sits 22 percent below the national figure of $64,400 a year, according to the same May 2025 data. Mississippi ranks 51st out of 51 states and the District of Columbia for LPN pay, the lowest in the country. Lower wages here generally track the state's lower cost of living. About 9,850 LPNs work in Mississippi, compared with 648,410 nationwide.

Entry-level positions in Mississippi typically offer around $18.91 an hour, or about $39,320 a year, for LPNs just starting out. Some newcomers land closer to $22.50 an hour, or $46,790 a year, depending on the employer and setting. Pay tends to move toward the state's typical figure of $24.14 an hour within the first few years on the job. Hospitals and larger facilities often pay more than smaller clinics for the same entry-level role.

Experienced LPNs in Mississippi often earn upwards of $27.90 an hour, or about $58,030 a year, once they've built up several years on the job. The top 10 percent make over $29.29 an hour, or $60,910 a year. That's a spread of $21,590 between entry-level and top pay. Setting, years of experience, and city all play a role in where an individual nurse lands within that range.

In 2015, LPNs in Mississippi had a typical annual wage of $36,230. By 2025, that figure had climbed to $50,220, a gain of $13,990 over the decade. That's a rise of 39 percent in ten years. The increase wasn't steady each year; pay dipped slightly in 2021 before climbing sharply in 2022 and continuing upward since.

Nationally, LPN pay rose 49 percent over the same ten years, a faster pace than Mississippi's gain. Even so, pay in Mississippi has moved up substantially, not just kept pace with inflation. Someone starting an LPN career in Mississippi today enters a field where wages have trended upward for most of the past decade. That doesn't guarantee future increases, but the recent direction has been favorable for practical nurses in the state.

Pay runs highest in the Gulfport and Biloxi metro areas, where LPNs earn $56,430 a year, or $27.13 an hour, figures that reflect each city's full metro area. That's about 12 percent above the state figure of $50,220. Jackson, the state's capital, pays a bit less at $53,510 a year, or $25.72 an hour.

Hattiesburg pays the least among the state's metro areas, with LPNs earning $48,350 a year, or $23.25 an hour. That leaves a spread of $8,080 between the highest- and lowest-paying cities. Jackson, with about 2,050 LPNs, employs more practical nurses than any other Mississippi metro area, even though its pay falls between the two extremes. As elsewhere, higher pay in cities like Gulfport and Biloxi tends to track higher local living costs.

Mississippi pays less than every state it borders. Tennessee LPNs earn the most among neighbors, at $58,870 a year, 17 percent above Mississippi's figure. Louisiana ($57,470), Alabama ($57,030), and Arkansas ($56,620) all pay 13 to 14 percent more as well. For a Mississippi LPN considering a move, licensure can often be transferred or endorsed into a nearby state rather than requiring a full new application.

LPNs in Mississippi typically earn $50,220 a year, or $24.14 an hour, though that's below every neighboring state. Pay has risen 39 percent over the past decade, adding nearly $14,000 to typical earnings. Readers weighing a move or a new license should check Mississippi's state licensing and registry page for current requirements, and compare city-level pages for local pay figures before deciding where to work.