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How Much Does a Medical Assistant Make in St. Louis, MO in 2026?

Typical pay for Medical Assistants in St. Louis, from federal wage data (May 2025), with the ten-year trend and how the city compares across Missouri.

$44,710
Typical pay a year
$21.50
Typical pay an hour
+11%
vs Missouri · -2% vs US
6,170
Medical Assistants employed in the area
Where Medical Assistant pay falls in St. Louis
from starting out to the top earners
$36,670
Starting out
$38,550
First years
$44,710
Typical
$47,600
Experienced
$48,620
Top 10%

BLS OES May 2025 · St. Louis metro area

A typical Medical Assistant in St. Louis, Missouri earns $21.50 per hour, or $44,710 per year, according to the latest government wage data for the area (May 2025). Calculated from the annual figure, that is roughly $3,726 a month. Entry-level positions typically offer around $36,670, and the top 10% of earners make over $48,620.

That pay is 11% above the Missouri figure of $40,440 and 2% below the national figure of $45,690. St. Louis ranks 2nd of 8 metro areas in Missouri for Medical Assistant pay. About 6,170 Medical Assistants work in the St. Louis area.

Medical Assistant pay in St. Louis at a glance

  • Typical pay is $21.50 an hour, or $44,710 a year.
  • That is 11% above the Missouri figure, ranking 2nd of 8 metro areas in the state.
  • Entry-level positions typically offer around $36,670; the top 10% make over $48,620.
  • Typical pay rose +56% from 2015 to 2025, against +42% for Missouri as a whole.

BLS OES May 2025

How much does a Medical Assistant make in St. Louis?

Pay in St. Louis runs from entry-level positions at around $17.63 an hour to more than $23.38 for the top 10% of earners. The table sets each career stage against the Missouri and national figures.

Medical Assistant pay by career stage in St. Louis

Medical Assistant pay by career stage in St. Louis
Career stageSt. LouisMissouriUnited States
Starting out$36,670$17.63 an hour$35,810$17.21 an hour$36,050$17.33 an hour
First years$38,550$18.53 an hour$37,380$17.97 an hour$38,470$18.50 an hour
Typical Medical Assistant$44,710$21.50 an hour$40,440$19.44 an hour$45,690$21.97 an hour
Experienced$47,600$22.88 an hour$46,600$22.40 an hour$49,180$23.65 an hour
Top 10%$48,620$23.38 an hour$48,360$23.25 an hour$59,310$28.52 an hour

BLS OES May 2025 · city figures cover the St. Louis area as BLS defines it

Medical Assistant pay growth in St. Louis

$44,710
2025 typical annual pay
+$2,080 vs 2024
2015
2016
2017
2018
2019
2020
2021
2022
2023
2024
2025

Typical (median) annual wage for Medical Assistants in the St. Louis area · BLS OES May estimates, 2015 to 2025 · hover a bar for the year-over-year change

In 2015, typical Medical Assistant pay in St. Louis was $28,570 a year. By 2025 it had reached $44,710, a change of +56%, compared with +42% for Missouri over the same years.

How St. Louis compares with other Missouri cities

Kansas City pays Medical Assistants the most in Missouri at $45,300 a year, $590 more than St. Louis. The lowest-paying area in the state is Joplin at $37,220.

Typical Medical Assistant pay by metro area in Missouri
#CityTypical payHourlyVs St. LouisMedical Assistants employed
1Kansas City$45,300$21.78+1%4,220
2St. Louis$44,710$21.50this city6,170
3Columbia$41,350$19.88-8%380
4St. Joseph$40,280$19.37-10%270
5Jefferson City$38,260$18.40-14%280
6Springfield$37,870$18.21-15%1,600
7Cape Girardeau$37,470$18.02-16%350
8Joplin$37,220$17.89-17%440

Every metro area in Missouri with Medical Assistant wage data · BLS OES May 2025 · Missouri typical pay $40,440

Is St. Louis a good place to work as a Medical Assistant?

-2%
vs national pay · +11% vs Missouri
6,170
Medical Assistants employed in the St. Louis area
4.6
Medical Assistant jobs per 1,000 jobs, vs about 5.3 nationally

Medical Assistant pay in St. Louis sits close to the national figure: $44,710 a year, 2% below the national rate. For every 1,000 jobs in the St. Louis area, about 4.6 are Medical Assistant positions; nationally, the figure is closer to 5.3. Medical Assistant jobs make up about the same share of the job market as they do across the country.

Frequently asked questions

How much does a Medical Assistant make in St. Louis, MO?
A typical Medical Assistant in St. Louis earns $44,710 a year, or $21.50 an hour, according to BLS wage data for May 2025. Entry-level pay runs about $36,670 and the top 10% earn over $48,620.
How much does a Medical Assistant make an hour in St. Louis?
Typical hourly pay for Medical Assistants in St. Louis is $21.50. Entry-level hourly pay runs about $17.63, and the top 10% earn over $23.38 an hour.
What is the starting pay for a Medical Assistant in St. Louis?
Entry-level Medical Assistant positions in St. Louis typically offer around $17.63 an hour, or $36,670 a year.
Is Medical Assistant pay in St. Louis higher than in the rest of Missouri?
St. Louis pay is 11% above the Missouri figure of $40,440 a year, ranking 2nd of 8 metro areas in the state. Kansas City pays the most in Missouri at $45,300.

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