How Much Does a Medical Assistant Make in Colorado in 2026?

A typical Medical Assistant in Colorado earns about $23.27 per hour ($48,400 per year), according to the latest government wage data (May 2025). Based on that annual figure, pay works out to roughly $4,033 a month or $931 a week. Those figures cover the full range of clinical and administrative medical assistant work across the state.

That figure runs 6% above the national typical pay of $45,690, placing Colorado 10th among the 51 states and D.C. for Medical Assistant pay. Roughly 13,160 Medical Assistants work across Colorado, compared with 817,870 nationwide. The higher pay lines up with Colorado's higher cost of living relative to many other states.

Entry-level positions in Colorado typically offer around $18.81 an hour ($39,130 a year), according to the same May 2025 data. Medical Assistants who are new to the field, or working in smaller practices, tend to start near this range. Pay generally moves toward the statewide typical figure of $48,400 within the first few years on the job.

Experienced Medical Assistants in Colorado often earn upwards of $28.73 an hour ($59,760 a year), and the top 10% of earners make over that figure. The gap between entry-level and top-tier pay comes to $20,630 a year. Setting, years of experience, and city all factor into where an individual medical assistant lands within that range.

Colorado's typical Medical Assistant pay has climbed from $32,780 in 2015 to $48,400 in 2025, a gain of $15,620. That amounts to a 48% rise over the decade, according to the same government wage data. The increase has been fairly steady year over year, with a larger jump between 2021 and 2022.

Nationally, typical Medical Assistant pay rose 49% over the same ten years, putting Colorado's gain almost in line with the country as a whole. That keeps Colorado's long-term growth close to the national pattern rather than far ahead or behind it. Pay for Medical Assistants in Colorado has moved up steadily over the past decade, though past growth is not a guarantee of future increases.

Pay runs highest in Centennial, where Medical Assistants typically earn $49,700 a year ($23.90 an hour), about 3% above the statewide figure. Denver and Aurora share that same figure, since they fall within the same metro area. Boulder follows closely at $48,590 a year ($23.36 an hour).

Grand Junction pays the least among the cities listed, at $44,390 a year ($21.34 an hour), putting the spread between the highest- and lowest-paying cities at $5,310. Centennial also holds the largest Medical Assistant workforce in the state, with 6,440 workers. Each figure reflects pay across the full metro area, and cities with higher pay tend to carry a higher cost of living.

Colorado's typical Medical Assistant pay of $48,400 outpaces every neighboring state in the data. Nebraska comes closest at $47,370, about 2% below Colorado, while Oklahoma trails furthest at $38,750, about 20% below. Arizona ($45,940), Utah, Wyoming, Kansas, and New Mexico all fall somewhere in between. A Medical Assistant certification or registration earned in Colorado can often be transferred or endorsed into a neighboring state, though requirements vary.

Medical Assistants in Colorado typically earn $48,400 a year ($23.27 an hour), according to the latest government wage data (May 2025), up 48% over the past decade. Pay varies by city and experience level, with Centennial paying the most and entry-level positions starting lower. Readers weighing a move into the field can check Colorado's licensing or registry requirements and compare local figures on individual city pages for a closer look at pay near them.